Restoring normoglycaemia: not so harmless
نویسنده
چکیده
Three independent studies of tight glucose control were recently stopped prematurely due to an excess mortality in the intensive treatment arm. This commentary briefly discusses the potential mechanisms and reminds the potential benefits of physiological stress hyperglycemia.
منابع مشابه
Cost-aware Vulnerability Prediction: the HARMLESS Approach
Society needs more secure software. But predicting vulnerabilities is difficult and existing methods are not applied in practical use due to various limitations. The goal of this paper is to design a vulnerability prediction method in a cost-aware manner so that it can balance the percentage of vulnerabilities found against the cost of human effort on security review and test. To this purpose, ...
متن کاملphagocytic and bactericidal functions of granulocytes in insulin dependent diabetic patients
Ten insulin dependent diabetic patients were maintained in normoglycaemia for 36 h with an artificial pancreas. Circulating polymorphonuclear leucocytes were extracted and incubated with staphylococcus before and after treatment; phagocytic and bactericidal activities were studied. Granulocytes from diabetic patients showed a decreased ability to absorb staphylococcus and a reduced capacity for...
متن کاملبررسی اکلوژن فیزیولوژیک
Generally speaking, when preserving and restoring the gnathostomatic system the dentist controls tooth morphology to insure proper distribution of stress. So, we restore a portion of a tooth or all the teeth in such a manner as to subject the associated parts of the system to the least stress. We evaluate our diagnosis and control it in our treatment. The treatment should be based on the scient...
متن کاملAll-Cause Mortality Risk in Australian Women with Impaired Fasting Glucose and Diabetes
AIMS Impaired fasting glucose (IFG) and diabetes are increasing in prevalence worldwide and lead to serious health problems. The aim of this longitudinal study was to investigate the association between impaired fasting glucose or diabetes and mortality over a 10-year period in Australian women. METHODS This study included 1167 women (ages 20-94 yr) enrolled in the Geelong Osteoporosis Study....
متن کاملBoyle, a most skeptical chemist.
Stec EM, Vannucci SJ, Smith QR: Blood-brain barrier glucose transporter: effects of hypoand hyperglycemia revisited. J Neurochem 1999; 72:238–47 42. Preiser J-C: Restoring normoglycemia: Not so harmless. Critical Care (London, England) 2008; 12:116 43. Wilson M, Weinreb J, Hoo GWS: Intensive insulin therapy in critical care: A review of 12 protocols. Diabetes Care 2007; 30:1005–11 44. Krinsley ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Critical Care
دوره 12 شماره
صفحات -
تاریخ انتشار 2008